Yunzhi - the proven complement to conventional therapy of serious illness Yunzhi has been used in traditional Chinese medicine for centuries to strengthen the body's immune system.
More recent scientific researches and clinical trials have proven that Yunzhi extract helps stimulate the immune system so that the body is better able to defend against the serious illness.
Yunzhi is an effective complementary treatment option for people with serious illness at various stages.
The main effects of Yunzhi (Coriolus Versicolor) published in research reports include: 1. Activation of immune cells such as: T-lymphocytes, B-lymphocytes, monocytes, macrophages, bone marrow cells, natural killer cells and lymphokine- activated cells
1,2,5.
2. Increase of antibodies and a variety of cytokines such as: interleukin -2, interleukin -6, interferon and TNF
2,9.
3. Restore immunological response depression derived from serious illness treatment back to normal level
2,5.
4. Enhance the body’s immunity
3,4 to reduce chance of infection
2,9.
5. Reduce the side effects of the treatment of serious illness, improve patient’s mental and health status
13.
6. Inhibit mutated cells proliferation
3,14.
7. Increase the survival rate of patients
3,7,11,12.
Oncozac® - ONCO-Z®* as the only ingredient, combines four major advancements: Oncozac®’s only ingredient ONCO-Z®*, was the first Chinese medicinal ingredient verified by United States Pharmacopeial Convention (USP)*
USP offers verification services for dietary supplement finished products, dietary ingredients, pharmaceutical ingredients, and excipients. Products and ingredients that meet all USP verification requirements mean:
• The ingredients are consistent in quality from batch to batch.
• The ingredients meet label or certificate of analysis claims for identity, strength, purity, and quality.
• The ingredients are prepared in accordance with accepted manufacturing practices.
Please click here to get more information. Better absorption - Extract of Oncozac® is highly water soluble1 and is thus readily absorbed by the body to provide better effects.
Absorbable peptidoglucan - Containing absorbable peptidoglucan(APG), Oncozac ® stimulate proliferation of immune cells such as white blood cells, bone marrow cells and macrophages to boost body immunity.
Higher potency ^ due to proprietary extraction and processing method - Unique extraction method and sophisticated freeze-drying process are used in the production of Oncozac® to ensure that active ingredients especially(APG) are not damaged and can be effectively extracted from Yunzhi. These production advances help enhanced the efficacy of Oncozac®.
Development standardization and testing - In addition to containing absorbable peptidoglucan(APG), Oncozac® was conducted with immunological tests to prove its efficacy in immunostimulation.
Every batch of Oncozac® has obtained safety reports of heavy metals and toxic elements, pesticide residues and microbial limit tests from the world-renowned independent testing laboratory SGS (H.K.) Ltd. Product safety and reliability are guaranteed.
Oncozac® can help alleviate the side-effects arising from treatments of serious illnesses includeing susceptibility to infection, reduction of immune cells, oral discomfort, hair loss, nausea and vomiting, loss of appetite, severe weight loss and pain.
Oncozac® supports patients to complete the entire course of therapy and therefore facilitates their recovery.
Oncozac® can help improve the physical and mental well-being of patients.
Continuous consumption of
Oncozac® can help to improve the immune system after conventional treatment.
Reference
1. Chu K.K.W., Chow A.H.L. (2006) Preparation and standardization of immunomodulatory pepdite-linked glucans with verifiable oral absorbability from coriolus versicolor. United States patent filing : US 7,048,932 B2
2. Chu K.K.W., Ho S.S.S., Chow A.H.L. (2002) Coriolus versicolor : a medical mushroom with promising immunotherapeutic values. J Clin Pharmacol, 42(9) : 976-84
3. King-Fai Cheng, Ping-Chung Leung (2008) General review of polysaccharopeptides (PSP) from c. versicolor : pharmacological and clinical studies. Cancer Therapy Vol. 6 : 117-30
4. Leung M.Y.K., Liu C., Koon J.C.M., Fung K.P. (2006) Polysaccharide biological response modifiers. Immunology Letters 105 : 104-14
5. Liu F., Ooi V.E.C., Fung M.C. (1999) Analysis of immunomodulating cytokines mRNAs in the mouse induced by mushroom polysaccharides. Life Sci. 64(12) : 1005-11
6. Nakazato H., Koike A., Saji S., Ogawa N., Sakamoto J. (1994) Efficacy of immunochemotherapy as adjuvant treatment after curative resection of gastric cancer. Lancet 343 : 1122-6
7. Ohwada S., Ogawa T., Makita F., Tanahashi F., Ohya T., Tomizawa N., Satoh Y., Kobayashi I., Izumi M., Takeyoshi I., Hamada K., Minagushi S., Togo Y., Toshihiko T., Koyama T., Kamio M (2006) Beneficial effects of protein-bound polysaccharide K. plus tegafur/uracil in patients with stage II or III colorectal cancer : analysis of immunological parameters . Oncology Reports 15 : 861-8
8. University Research Findings of APG’s immunostimulatory Effect on Lymphocytes comparing with two competitors’ products in the market, 2003 9. Tsukagoshi S., Hashimoto Y., Fugii G., Kabayashi H., Namoto K., Orita K. (1984) Krestin (PSK). Cancer Treatment Rev. 11 : 131-55
10. USP verification of dietary ingredients : ONCO-Z coriolus versicolor extract. Ver ref. no. : 1080100301
11. Wong L.Y. Eliza, Cheng K.F., Leung P.C. (2012) Efficacy of yunzhi (coriolus versicolor) on survival in cancer patients : systematic review and meta-analysis. Recent Patents on Inflammation & Allergy Drug Discovery 6 : 78-87
12. Yamashita K., Ougolkov A.V., Nakazato H., Ito K., Ohashi Y., Kitakata H., Yasumoto K., Omote K., Mai M., Takahashi Y., Minamoto T. (2007) Adjuvant immunochemotherapy with protein-bound polysaccharide K for colon cancer in relation to oncogenic beta-catenin activation. Dis Colon Rectum 50 : 1169-81
13. Zhong Y., Zou J., Zhang L.Y. (2001) Clinical observation on alleviating chemotherapy’s side effect of PSP in treating gastric carcinoma. Liaoning Journal of Traditional Chinese Medicine 28 : 668-9
14. Zhou Y.L., Hua J., Lin J., Tang K.X. (2007) Cytotoxic activities of coriolous versicolor (Yunzhi) extracts on human liver cancer and breast cancer cell line. Afr J. Biotechnol 6 : 1740-43
*Oncozac®’s only ingredient ONCO-Z® is the first Chinese medicinal ingredient verified in the dietary ingredient verification service of U.S. Pharmacopeial Convention10
^ Internal Research of comparison between different coriolus versicolor products in response to in vitro mitogenic activity
